Future of medicine
blood test
/NKp30/B7-H6
DIAGNOSTIC GAP
GIST diagnosis usually starts after a lesion is visible.
Current diagnosis depends on imaging, biopsy and pathology
A blood test that can flag risk before a lesion becomes clinically obvious.
GIST diagnosis usually starts after a lesion is visible.
Current diagnosis depends on imaging, biopsy and pathology
A blood test that can flag risk before a lesion becomes clinically obvious.
PROPOSED SOLUTION
Two biomarkers capture tumor and immune signals.
The combined pattern may provide more context than either marker alone.
Two biomarkers capture tumor and immune signals.
The combined pattern may provide more context than either marker alone.
Gist diagnostic concept
Soluble B7-H6
May reflect tumor-associated expression and shedding into blood.
TUMOR SIGNAL
NKp30
Measures receptor expression on circulating NK cells.
IMMUNE SIGNAL
Composite
diagnostic score
diagnostic score
Designed to support earlier referral and repeat monitoring.
COMBINED OUTPUT
BIOLOGICAL RATIONALE
B7-H6 and NKp30 reflect the tumor–immune interaction
The assay reads both tumor-associated B7-H6 and the NK-cell receptor that recognizes it.
